Relevance of shrinkage versus fragmented response patterns in rectal cancer.

Sonay Kus Ozturk,Cristina Graham Martinez,Kieran Sheahan,Desmond C Winter,Susan Aherne,Éanna J Ryan,Cornelis Jh van de Velde,Corrie Am Marijnen,Geke Ap Hospers,Annet Gh Roodvoets,Michail Doukas,David Mens,Cornelis Verhoef,Rachel S van der Post,Iris D Nagtegaal

Histopathology（2023）

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摘要

The heterogeneous nature of tumour response following CRT is reflected in fragmentation and shrinkage. In rectal cancer there is a predominance of the fragmented pattern, which is associated with advanced stage and less tumour regression. While not independently associated with survival, these reproducible patterns give insights into the biology of tumour response.

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关键词

neoadjuvant chemoradiation treatment,partial response,patterns of response,rectal cancer

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