Impact of sarcosine on diabetic retinopathy: Findings based on weighted gene co-expression network analysis and machine learning techniques.

Mingzhu Che,Zhezheng Xia,Depeng Jiang,Yanan Wang,Hui Wang,Yuxin Chen,Ziyi Wang,Yang Chen,Xinlv Zhang,Zejie Zhang,Chengnan Guo,Xiaoyu Zhang,Chao Zheng,Guangyun Mao

Diabetes, obesity & metabolism（2023）

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摘要

Serum sarcosine was inversely related to DR, especially in T2D patients with insufficient HDL-C. This study provides insights on a possible novel target for DR precision prevention and control, as well as a better understanding of the DR mechanism.

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关键词

Diabetic retinopathy,WGCNA,propensity score matching,sarcosine

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