Epigenetic control of cancer inflammation
Nature cell biology(2023)
摘要
The interaction of non-immune and immune cells in the tumour microenvironment (TME) determines the quality of the immune attack on nascent tumour cells. A new study in melanoma cells shows that specific histone variants dampen the expression of cytokine genes in cancer-associated fibroblasts, leading to an immunosuppressive TME.
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关键词
epigenetic control,cancer,inflammation
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