Menopausal transition in multiple sclerosis: relationship with disease activity and brain volume measurements.

Frontiers in neurology(2023)

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摘要
Menopause may be an adverse prognostic factor of MS. Our preliminary results suggest that menopause may facilitate cortical GM atrophy, probably due to a decline in the neuroprotective effects of estrogen, with negative effects on MS evolution.
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关键词
aging, brain atrophy, menopause, multiple sclerosis, neurodegeneration, oestrogen deprivation
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