Platelet lysate for expansion or osteogenic differentiation of bone marrow mesenchymal stem cells for 3D tissue constructs.

Luis Oliveros Anerillas,Mikael Wiberg,Paul J Kingham,Peyman Kelk

Regenerative therapy（2023）

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摘要

PLT is a superior alternative to FBS for the expansion of MSCs without compromising their subsequent differentiation capacity in 3D. However, differentiation in PLT is impaired. Thus, PLT can be used to reduce the time required to expand the necessary cell numbers for development of 3D tissue engineered MSC constructs.

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关键词

Foetal bovine serum,Human platelet lysate,Mesenchymal stem cells,Osteogenesis,3D

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