Prognostic Role of Unfolded Protein Response-Related Genes in Hepatocellular Carcinoma.

Shuqiao Zhang,Xinyu Li,Yilu Zheng,Hao Hu,Jiahui Liu,Shijun Zhang,Chunzhi Tang,Zhuomao Mo,Weihong Kuang

Current protein & peptide science（2023）

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摘要

This study identified two UPR molecular subtypes of HCC and developed a ten-gene HCC prognostic signature model (EXTL3, PPP2R5B, ZBTB17, CCT3, CCT4, CCT5, GRPEL2, HSP90AA1, PDRG1, and STC2), which can robustly forecast the progression of HCC.

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关键词

Hepatocellular carcinoma, unfolded protein response, prognosis, immune, NMF, UPR

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