Diversity of blaL1-like genes in Stenotrophomonas species: insights from genome analysis of publicly available genomesequencesgenome sequences

Antimicrobial agents and chemotherapy(2023)

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摘要
L1 metallo-ss-lactamases produced by Stenotrophomonas maltophilia exhibit high diversity. Here, we characterized the genomes of Stenotrophomonas species harboring blaL(1-like) genes using publicly available genome sequences. Our findings provide evidence that Stenotrophomonas species with bla(L1-like) genes constitute a complex comprising many species with high genetic diversity, and similarities between blaL1- like genes are lower than those of the genome. This suggests that the diversity of blaL1- like is attributable to species diversity in Stenotrophomonas species harboring blaL1- like and the rapid evolutionary changes in bla(L1-like) genes.
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关键词
L1, Stenotrophomonas, diversity
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