High expression of autophagy-related gene EIF4EBP1 could promote tamoxifen resistance and predict poor prognosis in breast cancer.

Shan Yang,Tian-Li Hui,Hao-Qi Wang,Xi Zhang,Yun-Zhe Mi,Meng Cheng,Wei Gao,Cui-Zhi Geng, Sai-Nan Li

World journal of clinical cases（2023）

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摘要

This study indicated that EIF4EBP1 was overexpressed in the BC and TAM-resistant cell line, which increased cell proliferation, invasion, migration and TAM resistance in BC cells.

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关键词

tamoxifen resistance,breast cancer,gene,autophagy-related

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