Clostridium ventriculi in a cynomolgus monkey with acute gastric dilatation and rupture: A case report

JOURNAL OF MEDICAL PRIMATOLOGY(2024)

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摘要
Acute gastric dilatation (AGD) is one of the most prevalent and life-threatening diseases in nonhuman primates worldwide. However, the etiology of this syndrome has not been determined. Recently, sudden death occurred in a 7-year-old female cynomolgus monkey with a history of fecal microbiota transplantation using diarrheic stools. The monkey had undergone surgery previously. On necropsy, gastric dilatation and rupture demonstrated a tetrad arrangement on histopathologic examination. On 16S rRNA sequencing, a high population of Clostridium ventriculi was identified in the duodenum adjacent to stomach but not in the colon. This paper is the first report of Clostridium ventriculi infection in a cynomolgus macaque with acute gastric dilatation and rupture.
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关键词
acute gastric dilatation and rupture,Clostridium ventriculi,cynomolgus monkey,microbiome
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