Novel human lymph node-derived matrix supports the adhesion of metastatic oral carcinoma cells.

Erika Naakka,Wafa Wahbi, Riia Tiikkaja,Krista Juurikka, Toni Sandvik,Petri Koivunen,Timo Autio, Jukka Tikanto, Janne Väisänen,Hannu Tuominen,Anne Talvensaari-Mattila,Ahmed Al-Samadi,Rabah Soliymani,Pirjo Åström,Maija Risteli,Tuula Salo

BMC cancer（2023）

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摘要

We demonstrated that human pre-metastatic neck lymph node-derived matrix is suitable for studying metastatic OTSCC cells. As a whole-protein extract, h-LG provides new opportunities for in vitro carcinoma cell culture experiments.

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关键词

Myogel,Lymphogel,Lymph nodes,Oral tongue squamous cell carcinoma,Tumour microenvironment

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