Diarrheal-associated gut dysbiosis in cancer and inflammatory bowel disease patients is exacerbated by Clostridioides difficile infection.

Maria Kulecka,Natalia Zeber-Lubecka,Aneta Bałabas,Paweł Czarnowski,Katarzyna Bagińska,Maria Głowienka,Anna Kluska,Magdalena Piątkowska,Michalina Dąbrowska,Edyta Waker,Michał Mikula,Jerzy Ostrowski

Frontiers in cellular and infection microbiology（2023）

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摘要

Our data indicate that different external and internal factors drive comparable profiles of low diversity dysbiosis. While diarrheal-related low diversity dysbiosis may be a consequence of systemic cancer therapy, a similar phenotype is observed in cases of moderate to severe IBD, and in both cases, dysbiosis is exacerbated by incidence of CDI.

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关键词

gut dysbiosis,inflammatory bowel disease,difficile infection,clostridioides,inflammatory bowel disease patients,diarrheal-associated

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