Does hyperthermic povidone-iodine lavage increase the apoptotic rate of residual cancer cell in patients with malignant pleural mesothelioma?-a prospective pilot study.

Andrea Bille, Hiral Jhala, Leanne Ashrafian, Leanne Allison, Matthew Russell,Roland Fleck,Daisuke Nonaka

Translational lung cancer research(2023)

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摘要
Although hyperthermic betadine lavage is a safe antiseptic solution with no toxicity when performed intraoperatively, it confers no effect on apoptotic rate or necrosis. It is therefore unlikely that hyperthermic betadine lavage will have an impact on reducing the microscopic residual disease after pleurectomy decortication and enhancing survival.
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apoptotic rate,cancer cell,residual cancer cell,povidone-iodine
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