Radiation damage to biological macromolecules∗.
Current opinion in structural biology（2023）
摘要
In this review, we describe recent research developments into radiation damage effects in macromolecular X-ray crystallography observed at synchrotrons and X-ray free electron lasers. Radiation damage in small molecule X-ray crystallography, small angle X-ray scattering experiments, microelectron diffraction, and single particle cryo-electron microscopy is briefly covered.
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关键词
Radiation damage, Reduction, X-ray free electron lasers, X-rays, Dose, Global damage, Specific structural damage, Disulphide bond breakage, Synchrotrons, Electrons, Microscopy
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