SERPINB5 is a novel serum diagnostic biomarker for gastric high-grade intraepithelial neoplasia and plays a role in regulation of macrophage phenotypes

Xiuhong Huang,Xiaoli Xie,Ning Kang,Ran Qi,Xue Zhou,Yijun Wang,Huiqing Jiang

Translational oncology（2023）

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摘要

•SERPINB5 is a biomarker of gastric high-grade intraepithelial neoplasia.•Serum SERPINB5 has good diagnostic efficacy.•SERPINB5 regulates macrophage phenotypes conversion.

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关键词

SERPINB5,Biomarker,Noninvasive,Gastric precancerous lesions,Macrophages

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