Elevated serum mitochondrial DNA levels were associated with the progression and mortality in idiopathic pulmonary fibrosis

Yi Liang, Shiwen Fan, Yuxian Jiang, Tong Ji,Ranxun Chen,Qingqing Xu,Yin Liu,Yonglong Xiao,Hourong Cai,Jinghong Dai

International immunopharmacology（2023）

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摘要

•Elevated serum mitochondrial DNA levels were associated with the progression and mortality of IPF.•Mitochondrial DNA levels appear to correlate with serum albumin levels in IPF patients.•Cellular and systemic interplay of metabolism and inflammation in the pathogenesis of IPF.

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关键词

IPF,Mitochondrial DNA,Albumin,Disease progression,Mortality

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