Androgen receptor and MYC transcriptomes are equilibrated in multilayer regulatory circuitries in prostate cancer.

Bin Fu,Liyang Wang,Tianwei Jia,Zhao Wei,Nuosu Nama,Jiaqian Liang, Xinghua Liao,XiaMing Liu,Yanfei Gao,Xiaoqiang Liu, Raymond S Mao,Keshan Wang,Ju Guo,Shaoyong S Chen

The Prostate（2023）

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摘要

Together, our findings stratified AR-MYC interactions that are extensively wired and intricately organized to compensate for essential PCa transcriptional programs and neutralize excessive signaling.

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关键词

prostate cancer,myc transcriptomes,multilayer regulatory circuitries,receptor

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