Curcumin modulates astrocyte function under basal and inflammatory conditions

Marina Seady,Fernanda Telles Fróes,Carlos Alberto Gonçalves,Marina Concli Leite

Brain research（2023）

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摘要

•Piperine prevented GFAP increase induced by LPS in astrocytes.•Curcumin and piperine prevented the TNF-α secretion induced by LPS in astrocytes.•Astrocytes are key cells in the neuroinflammatory response.•Curcumin increased GFAP and GSH content in astrocytes.•Curcumin reduced the secretion of S100B protein in astrocytes.

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关键词

Astrocyte,Curcumin,LPS,Neuroinflammation,Piperine,S100B

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