Profiling the Ca 2+ spark dynamics in live cardiomyocytes

Laetitia Pereira,Almudena Val-Blasco,Jean-Pierre Benitah,Ana M. Gómez

Nature Cardiovascular Research（2023）

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摘要

Calcium sparks are the elementary detectable units of calcium release through ryanodine receptors (RyRs). Hou et al. correlate Ca 2+ sparks with RyR cluster configurations and provide insights into the dynamics of Ca 2+ release in live cardiomyocytes at baseline and in pathological conditions.

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关键词

Cardiovascular biology,Cellular imaging,Electrophysiology,Cardiovascular Biology

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