Early adjustment of levothyroxine treatment in pregnancy
Nature Reviews Endocrinology（2010）
摘要
The THERAPY trial investigators conclude that, when pregnancy is confirmed in adequately treated women with hypothyroidism, doubling the dose of prepregnancy levothyroxine on 2 days each week safely prevents maternal hypothyroidism in the first trimester of pregnancy in most cases. Is this really the best strategy to adopt?
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