Long-Term Effects on Retinal Structure and Function in a Mouse Endothelin-1 Model of Retinal Ganglion Cell Degeneration.

Yamunadevi Lakshmanan,Francisca Siu Yin Wong,Henry Ho-Lung Chan

Investigative ophthalmology & visual science（2023）

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摘要

ET-1 injection in mice resulted in a transient vascular constriction and reduction in retinal functions, as well as a gradual loss of retinal nerve fiber layer and RGC in a dose-dependent manner.

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关键词

endothelin-1, mice model, electroretinogram, OCT, doppler flow

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