Oral gonadotrophin-releasing hormone (GnRH) antagonists: the continuing search for the ideal nonsurgical therapy of uterine fibroids with a cautionary tale.

Ogagaoghene Sim-Ifere,Mehrnoosh Aref-Adib,Funlayo Odejinmi

Current opinion in obstetrics & gynecology(2023)

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摘要
This article highlights the uses of GnRH antagonists in practice and reflects on previous novel treatments for fibroids with a focus on Ulipristal acetate. It states the importance of using audit tools and multiinstitutional databases to prevent and allow early discovery of issues such as those that encumbered Ulipristal.
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关键词
add-back therapy, gonadotrophin-releasing hormone antagonists, heavy menstrual bleeding, ulipristal acetate
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