Fast-response electrochemical biosensor based on a truncated aptamer and MXene heterolayer for West Nile virus detection in human serum

Hanbin Park, Nayeon Kwon,Goeun Park,Moonbong Jang,Yein Kwon,Yejin Yoon,Jeongyun An,Junhong Min,Taek Lee

Bioelectrochemistry (Amsterdam, Netherlands)（2023）

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摘要

•The biosensor is composed of a MXene/Tr-WNV aptamer bilayer structure.•Application of ACEF significantly decreases WNV detection time to 10 min.•Aptamer truncation process increased specificity and reduced manufacturing cost.•Th2is biosensor exhibits promising potential for diagnosing WNV-related diseases.

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关键词

Aptamer truncation,West Nile virus,ACEF,Rapid biosensor,Electrochemical biosensor,SELEX

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