Sarcoid-like reaction in a child following prolonged therapeutic exposure to dabrafenib and trametinib for BRAF V600E mutated hypothalamic/chiasmatic glioma

LETTER TO THE EDITORTITLE: Sarcoid-like reaction in a child following prolonged therapeutic exposure to dabrafenib and trametinib for BRAF V600E mutated hypothalamic/ chiasmatic gliomaAuthors : Mari Wilhelmsson MD, PhD1,2; Foo Jen Chun MD1; Rae S M Yeung MD, PhD3; Fiona Krtizinger MBChB, MMed4; Tata McKeown, MSc1; Ailish Coblentz, MD5; Birgit Ertl-Wagner, MD5; Uri Tabori MD, PhD1, Ute Bartels MD, PhD 1; Anirban Das MBBS, MD, DM 1AFFILIATIONS: 1. Division of Haematology Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada; 2. Department of Women´s and Children´s Health, Karolinska Institutet, Stockholm, Sweden. 3. Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario, Canada. 4. Division of Respiratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada. 5. Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada.WORD COUNT: 853FIGURES: 1RUNNING TITLE: Sarcoid-like reaction with BRAF/MEK-inhibitionKEYWORDS : MEK-inhibitor, BRAF inhibitor, sarcoidosis/sarcoid‑like reaction (S/SLR), Low-grade glioma, pediatric