Circulating miR-221/222 expression as microRNA biomarker predicting tamoxifen treatment outcome: a case-control study.

Ilhamjaya Patellongi, Alfiah Amiruddin, Muhammad N Massi,Andi A Islam, Muhammad Y Pratama,Noorwati Sutandyo, Nani H M Latar,Muhammad Faruk

Annals of medicine and surgery (2012)（2023）

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摘要

The use of circulating miR-221/222 expression can predict relapse as well as resistance to tamoxifen treatment in BC patients, and their testing is recommended for luminal subtype BC patients who will undergo tamoxifen therapy to determine their risk of tamoxifen resistance early, increasing treatment effectiveness.

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关键词

breast cancer, luminal, miR-221, miR-222, tamoxifen

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