Nucleolin promotes tumor growth in colorectal cancer by enhancing hnRNPA1-mediated PKM2 alternative splicing.
Genes & diseases(2023)
摘要
Emerging evidence indicates that metabolism reprogram-ming plays an important role in cancer progression.RNA-binding protein nucleolin(NCL)was reported to function as an important oncogenic factor in multiple cancer types.1 However,the role and mechanism of NCL in cancer metabolism are unknown.
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