The potential development of drug resistance in rheumatoid arthritis patients identified with p53 mutations.

Congling Qiu,Joyce Tsz Wai Chan, David Wei Zhang,Io Nam Wong,Yaling Zeng,Betty Yuen Kwan Law,Simon Wing Fai Mok,Ivo Ricardo De Seabra Rodrigues Dias,Wenfeng Liu,Liang Liu,Vincent Kam Wai Wong

Genes & diseases（2023）

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摘要

Rheumatoid arthritis(RA)is a chronic inflammatory disease characterized by cartilage and bone damage with the presence of pannus formation which causes uncontrollable proliferation and invasion of fibroblast-like synoviocytes(FLS).

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关键词

rheumatoid arthritis,rheumatoid arthritis patients,drug resistance,p53

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