Germline chek2 mutated mds patients

L. Freiman, L. Larcher, G. Tueur, N. Vasquez, M. Da Costa,E. Raffoux,L. Ades, P. Fenaux, S. Jean, N. Duployer,E. Clappier, M. Sebert

LEUKEMIA RESEARCH(2023)

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摘要
The study includes the perpetration and characterization of new ligand of β-enaminone with its mixed ligands complexes of first transition element ions which their formula are [(M)(L1)(8.h.q)]; M = [Co(II), Ni(II), Cu(II), Zn(II) and Cd(II)]. The prepared ligand and its complexes were diagnosed by the (FT-IR) furrier transform infrared spectroscopy, (Uv–vis) ultraviolete-visible spectroscopy, (1H-, 13C NMR Nuclear magnetic resonance spectroscopy or Resonanse), mass spectroscopy, melting point, thin film chromatography on thin layer chromatoraphy, and (CHNS) analysis. The results prove that the ligand behave as bidentate chelating through the exocyclic oxygen and nitrogen atoms.“
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germline chek2,patients
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