免疫微环境促进垂体神经内分泌肿瘤侵袭的研究进展
Chinese Journal of Neurosurgery（2023）
Abstract
垂体神经内分泌肿瘤是一种常见的颅内肿瘤，部分垂体神经内分泌肿瘤表现出侵袭性行为，可累及蝶窦、海绵窦、鞍上，甚至颅底硬脑膜及斜坡等周围组织，导致手术全切除率低、复发率高，亟需更有效的治疗措施。免疫微环境是肿瘤细胞赖以生存的局部环境，对其的研究有助于了解垂体神经内分泌肿瘤发生、发展、侵袭的机制，并发现新的免疫治疗靶点。本文针对免疫微环境促进垂体神经内分泌肿瘤侵袭性的相关研究进行了综述。
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