Dietary, Herbal and Nutritional Interventions for Managing Rheumatoid Arthritis: A Review

Rheumatoid Arthritis (RA) is a systemic, inflammatory disease that affects joints andleads to progressive cartilage and bone deterioration. The susceptibility to RA is determined bygenetic and environmental factors. Recently, many efforts have been undertaken to develop naturalcompounds capable of reducing the symptoms of RA to avoid the negative effects of the currentanti-inflammatory drugs. Interestingly, substantial data has revealed that nutritional, and herbalsupplements may be effective adjuvants in reducing the symptoms of RA by influencing thepathogenic inflammatory processes. In this context, various kinds of food, phenolic substances,spices like ginger, and turmeric, several vitamins, and probiotics are reported to control the activityof inflammatory molecules implicated in the pathophysiology of RA and therefore, have provedsuccessful in slowing the course of this arthritic illness. Therefore, the goal of this review article isto compile various findings on RA that have revealed illuminating information about the antiinflammatory,antioxidant, analgesic, immunomodulatory, and bone erosion-preventing propertiesof nutritional, and herbal components. Conclusively, this review concentrates on natural ingredientsthat may enhance overall well-being, promote health, and lessen the risk of RA.