Platform adaptive trial of novel antivirals for early treatment of COVID-19 In the community (PANORAMIC): protocol for a randomised, controlled, open-label, adaptive platform trial of community novel antiviral treatment of COVID-19 in people at increased risk of more severe disease. Oghenekome Gbinigie , Emma Ogburn , Julie Allen , Jienchi Dorward , Melissa Dobson , Tracie-Ann Madden , Ly-Mee Yu , David M Lowe , Najib Rahman , Stavros Petrou , Duncan Richards , Kerenza Hood , Mahendra Patel , Benjamin R Saville , Joe Marion , Jane Holmes , May Ee Png , Gail Hayward , Mark Lown , Victoria Harris , Bhautesh Jani , Nigel Hart , Saye Khoo , Heather Rutter , Jem Chalk , Joseph F Standing , Judith Breuer , Layla Lavallee , Elizabeth Hadley , Lucy Cureton , Magdalena Benysek , Monique I Andersson , Nick Francis , Nicholas P B Thomas , Philip Evans , Oliver van Hecke , Mona Koshkouei , Maria Coates , Sarah Barrett , Clare Bateman , Jennifer Davies , Ivy Raymundo-Wood , Andrew Ustianowski , Jonathan Nguyen-Van-Tam , Andrew Carson-Stevens , Richard Hobbs , Paul Little , Christopher C Butler BMJ open(2023)
摘要
ISRCTN30448031; EudraCT number: 2021-005748-31.
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antivirals treatment, novel antivirals, adaptive platform trial, adaptive trial, open-label
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