A Novel Small Molecule Inhibitor of p38⍺ MAP Kinase Augments Cardiomyocyte Cell Cycle Entry in Response to Direct Cell Cycle Stimulation.

Riham R E Abouleisa,Jessica M Miller,Ahmad Gebreil,Abou Bakr M Salama, Marc Dwenger,Hania Abdelhafez,Reham M Wahid,Adeniyi T Adewumi,Mahmoud E S Soliman,Nader E Abo-Dya,Tamer M A Mohamed

British journal of pharmacology（2023）

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摘要

NDPPC is a novel inhibitor for p38 MAP kinase and is a promising drug to augment CM cell cycle response to the 4F. NDPPC could become an adjunct treatment with other cell cycle activators for heart failure treatment.

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关键词

cardiomyocyte cell cycle entry,kinase,direct cell cycle stimulation,cell cycle,novel small molecule inhibitor

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