A Pregnant Woman With Hypercalcemia-Induced Acute Pancreatitis.

Hypercalcemia in pregnancy represents a challenge for the clinician. It is an uncommon condition with associated maternal and fetal complications. Diagnosing hypercalcemia is complex in pregnancy because symptoms are not specific and may mimic those in early pregnancy. Etiologic assessment and therapeutic management must also respect the fetal well-being.1 CYP24A1 loss of function leads to the overproduction of calcitriol, which can result in hypercalcemia. CYP24A1 screening should be considered in non-parathyroid hormone (PTH) hypercalcemia during pregnancy; particularly as pregnancy may exacerbate hypercalcemia in mutation carriers.