Downregulation of lysosomal trafficking in ARPE19 cells leads to decreased transfection efficiency at high passage.

Erika M S Hood,Rachel A Jones Lipinski,Daniel M Lipinski

bioRxiv : the preprint server for biology（2023）

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摘要

This study contributes to mounting evidence for changes in ARPE19 cell physiology with increasing passage number. This information is of value for the continued use of ARPE19 cells as a model system for RPE biology and the development of therapeutics.

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