Association of NOTCH4 and ACHE gene polymorphism in Alzheimer’s disease of Gujarat cohort

Neuroscience letters(2023)

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摘要
•19 variants of 16 genes showed significant association with Alzheimer’s disease.•Functional enrichment showed significant enrichment to Alzheimer’s Disease.•rs367398/NOTCH4 and rs1799806/ACHE showed significant eQTL for neighbouring genes.
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关键词
Alzheimer’s disease,Targeted sequencing,Single nucleotide polymorphism,Association analysis
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