Patient-specific iPSC-derived cardiomyocytes reveal variable phenotypic severity of Brugada syndrome.

Yaxun Sun,Jun Su,Xiaochen Wang,Jue Wang,Fengfeng Guo,Hangyuan Qiu,Hangping Fan,Dongsheng Cai,Hao Wang,Miao Lin,Wei Wang,Ye Feng,Guosheng Fu,Tingyu Gong,Ping Liang,Chenyang Jiang

EBioMedicine（2023）

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摘要

National Key R&D Program of China (2017YFA0103700), National Natural Science Foundation of China (81922006, 81870175), Natural Science Foundation of Zhejiang Province (LD21H020001, LR15H020001), National Natural Science Foundation of China (81970269), Key Research and Development Program of Zhejiang Province (2019C03022) and Natural Science Foundation of Zhejiang Province (LY16H020002).

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关键词

iPSC-CMs,Brugada syndrome,SCN5A,Asymptomatic mutation carriers,Calcium current

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