Pentraxin 3 deficiency ameliorates the severity of osteoarthritis and alleviates inflammation.

Cheng Qiu,Jingwei Liu,Jinghang Li, Derun Di,Manyu Li,Tianyi Liu,Xinyu Wang,Yunpeng Zhao,Lianlei Wang,Xinyu Liu

Biochemical and biophysical research communications（2023）

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摘要

Pentraxin 3 deficiency significantly ameliorated the severity of osteoarthritis by preventing cartilage degeneration and alleviated systematic inflammation by inducing M2 polarization.

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关键词

Pentraxin 3,Inflammation,Osteoarthritis,Macrophage,Cartilage

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