Usage Trends and Safety Profile of Recombinant Human Bone Morphogenetic Protein-2 for Spinal Column Tumor Surgery: A National Matched Cohort Analysis.

Mohammed A Munim,Elyse Berlinberg,Vincent P Federico,Michael T Nolte,Michael Prabhu,Hanna Pawlowski,Karan S Patel,Matthew W Colman

Global spine journal（2023）

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摘要

This analysis demonstrated significantly declining national utilization rates. Spinal tumor cases utilizing rhBMP-2 sustained greater rates of surgical site and systemic infections. rhBMP-2 usage did not significantly reduce the risk of mortality, implant failure, or reoperation.

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关键词

bone graft, fusion, tumor, tumors, metastases, basic science, bone morphogenetic protein

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