Rheumatoid factor isotypes in rheumatoid arthritis diagnosis and prognosis: a systematic review and meta-analysis.

Francesca Motta,Nicola Bizzaro,Davide Giavarina,Franco Franceschini,Maria Infantino,Boaz Palterer,Gian Domenico Sebastiani,Carlo Selmi

RMD open（2023）

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摘要

Testing RF allows the highest sensitivity, while IgA isotype the highest specificity and positive likelihood ratio for RA diagnosis. On the other hand, determination of RF isotypes dose not allow prognostic information, as data are limited and heterogeneous.

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关键词

rheumatoid factor, arthritis, rheumatoid, autoantibodies

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