DNA methylation profiling in Trisomy 21 females with and without breast cancer.

Yosra Bejaoui,Sara Alresheq,Sophie Durand, Marie Vilaire-Meunier,Louise Maillebouis,Ayman Al Haj Zen,André Mégarbané,Nady El Hajj

Frontiers in oncology（2023）

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摘要

This is the first study to investigate DNA methylation changes in Down syndrome women with and without breast cancer and it could help shed light on factors that protect against breast cancer in DS.

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关键词

Down syndrome, breast cancer, DNA methylation, epigenetics, Trisomy 21

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