GOLD stage-specific phenotyping of emphysema and airway disease using quantitative computed tomography.

Philip Konietzke, Christian Brunner,Marilisa Konietzke,Willi Linus Wagner,Oliver Weinheimer,Claus Peter Heußel,Felix J F Herth,Franziska Trudzinski,Hans-Ulrich Kauczor,Mark Oliver Wielpütz

Frontiers in medicine（2023）

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摘要

QCT parameters showed a significant increase of emphysema from GOLD 0-4 COPD. Airway changes showed a different spatial pattern with higher values of relative wall thickness in the lower lobes until GOLD 2 and subsequent lower values in GOLD3/4, whereas there were no significant differences in the upper lobes. Both, EI and WP are independently correlated with lung function decline.

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关键词

chronic obstructive pulmonary disease (COPD), quantitative CT (QCT), GOLD stages, airway disease, lung emphysema

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