Urinary biomarkers of kidney tubule health and mortality in individuals with chronic kidney disease and diabetes mellitus.

George Vasquez-Rios,Ronit Katz,Emily B Levitan,Mary Cushman,Chirag R Parikh,Paul L Kimmel,Joseph V Bonventre,Sushrut S Waikar,Sarah J Schrauben,Jason H Greenberg,Mark J Sarnak,Joachim H Ix,Michael G Shlipak,Orlando M Gutierrez

Kidney360（2023）

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摘要

Among persons with diabetes and CKD, higher urine KIM-1 and YKL-40 were associated with a higher risk of all-cause mortality independently of established risk factors. Urine UMOD and MCP-1 were associated with cardiovascular- and cancer-related death, respectively.

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