Reply to Ren et al.: The role of a liver-specific mitochondrial carrier SLC25A47 in glucose homeostasis.

Recent studies have shown that the human mitochondrial proteome is enriched for small proteins with vital cellular functions. We describe here a primate-specific small mitochondrial protein NERCLIN as a negative regulator of cardiolipin ...Cardiolipin (CL) is an essential phospholipid for mitochondrial structure and function. Here, we present a small mitochondrial protein, NERCLIN, as a negative regulator of CL homeostasis and mitochondrial ultrastructure. Primate-specific NERCLIN is ...