High-fat diet-induced obesity accelerates the progression of spontaneous osteoarthritis in Senescence-Accelerated Mouse Prone 8 (SAMP8).

Chenyang Ding,Dilimulati Yimiti,Yohei Sanada,Yuki Matsubara,Tomoyuki Nakasa,Kiminori Matsubara,Nobuo Adachi,Shigeru Miyaki

Modern rheumatology（2023）

引用 0|浏览6

暂无评分

摘要

Ten weeks of HFD feeding promotes spontaneous OA progression in 14-week-old SAMP8, potentially via liver damage subsequent chondrocyte apoptosis. This aging-obese mouse model may prove valuable for further exploration of spontaneous OA pathophysiology.

查看译文

关键词

Apoptosis, high-fat diet, obesity, osteoarthritis, SAMP8

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要