Prevalence of neurocognitive disorder in Huntington's disease using the Enroll-HD dataset.

Luis A Sierra,Clementina J Ullman,Clara Baselga-Garriga,Sarbesh R Pandeya,Samuel A Frank,Simon Laganiere

Frontiers in neurology（2023）

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摘要

The prevalence of NCD in HD is elevated in preHD and demonstrates a sharp rise prior to diagnosis. In manifest HD, the vast majority of participants meet criteria for NCD. These findings are important for optimizing clinical care and/or anticipating the need for supportive services.

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关键词

Huntington's disease, cognition, neurocognitive disorders (NCD), pre-motor manifest, DSM-5

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