Development and validation of prognostic risk prediction models for hepatocellular carcinoma patients treated with immune checkpoint inhibitors based on a systematic review and meta-analysis of 47 cohorts.

Frontiers in immunology(2023)

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摘要
Based on the meta-analysis, we successfully constructed the OS and PFS prediction models for ICI-treated HCC patients. We also validated the models externally and observed good discrimination and calibration. The model's selected indicators are easily obtainable, making them suitable for further application in clinical practice.
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关键词
hepatocellular carcinoma patients,hepatocellular carcinoma,immune checkpoint inhibitors,prognostic risk prediction models,risk prediction,meta-analysis
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