Application of FT-IR Spectroscopy for Mycobacterium abscessus complex subspecies differentiation.

Antonio Curtoni,Miriam Cordovana,Alessandro Bondi,Francesca Scaiola,Giulia Criscione,Davide Ghibaudo, Lisa Pastrone,Elisa Zanotto, Anna Camaggi, Maria Simona Caroppo,Markus Kostrzewa,Rossana Cavallo,Cristina Costa

Journal of microbiological methods（2023）

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摘要

Mycobacterium abscessus complex (MABSC) subspecies differentiation improves patients' therapy and outcome. Fourier-Transform-Infrared Spectroscopy (FT-IRS) was applied for subspecies discrimination of 15 strains on different media: Löwenstein-Jensen showed the best resolution power; Linear Discriminant Analysis model differentiated M. abscessus susbsp. abscessus from M. abscessus subsp. massiliense. FT-IRS has a potential role in rapidly MABSC subspecies identification.

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