216P Relationship between regulatory T lymphocytes (Treg): Related genes and pathological response to neoadjuvant docetaxel-carboplatin in early-stage triple-negative breast cancer (TNBC)

R. Martín Lozano, M. Roche-Molina,E. Alvarez, M. Del Monte-Millan, Y. Jerez Gilarranz,F. Moreno Anton,J.Á. García Saenz,I. Echavarria Diaz-Guardamino, T. Massarrah, M. Cebollero,A.I. Ballesteros Garcia,U. Bohn Sarmiento,H.L. Gomez Moreno, H.A. Fuentes, B. Herrero Lopez,S. Gamez Casado, C. Bueno Muiño, O. Bueno, S. Lopez-Tarruella Cobo,M. Martin Jimenez

Immuno-Oncology and Technology（2022）

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摘要

An immune infiltrate rich in Treg is associated with worse prognosis in breast cancer, although there is controversy regarding their role and clinical relevance among the different tumor subtypes. This project aims to analyze the expression of Treg-related genes and its relationship with pathological response to neoadjuvant docetaxel-carboplatin in a cohort of patients with early-stage TNBC.

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关键词

breast cancer,treg,docetaxel-carboplatin,early-stage,triple-negative

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