Long-term effects of streptozotocin-induced gestational diabetes mellitus on mechanical sensitivity and intraepidermal nerve fibers in female and male mice offspring

Enriqueta Muñoz-Islas, Dehni Irasema Vargas-Balderas, Ivanna Hernandez, Juan Antonio Vazquez-Mora,Rosa Issel Acosta-González,Juan Miguel Jiménez-Andrade

NEUROSCIENCE LETTERS（2023）

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摘要

•The mechanical sensitivity and intraepidermal density were assessed in middle-aged offspring of dams with GDM.•Middle-aged offspring had greater mechanical sensitivity and lower intraepidermal CGRP+ and PGP9.5+ density.•GDM effects on middle-aged offspring are sex independent.

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关键词

GDM,Offspring,Long-term outcomes,Mechanical sensitivity,Nerve fibers

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