Replication of a neuroimaging biomarker for striatal dysfunction in psychosis.

Jose Rubio,Todd Lencz,Hengyi Cao, Nina Kraguljac, Elvisha Dhamala,Philipp Homan,Guillermo Horga,Deepak Sarpal,Miklos Argyelan,Juan Gallego,John Cholewa,Anita Barber,John Kane, Anil Maholtra

Research square（2023）

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摘要

To bring biomarkers closer to clinical application, they should be generalizable, reliable, and maintain performance within the constraints of routine clinical conditions. The functional striatal abnormalities (FSA), is among the most advanced neuroimaging biomarkers in schizophrenia, trained to discriminate diagnosis, with post-hoc analyses indicating prognostic properties. Here, we attempt to replicate its diagnostic capabilities measured by the

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Biomarker,Early Psychosis,Neuroimaging

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