miR-4739 promotes epithelial-mesenchymal transition and angiogenesis in "driver gene-negative" non-small cell lung cancer via activating the Wnt/β-catenin signaling.

Wenjian Cen, Qin Yan,Wenpeng Zhou,Minjie Mao,Qitao Huang,Yaobin Lin,Neng Jiang

Cellular oncology (Dordrecht)（2023）

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摘要

Our work identifies a valuable oncogene, miR-4739, that accelerates malignant progression in "driver gene-negative" NSCLC and serves as a potential therapeutic target for this group of tumors.

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关键词

Angiogenesis,Driver gene,EMT,Exosome,miR-4739

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